Recombinant GZMB 抗体 (AA 19-247)
Quick Overview for Recombinant GZMB 抗体 (AA 19-247) (ABIN7449554)
抗原
See all GZMB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 19-247
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原理
- Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
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免疫原
- residues 19-247 (mature protein)
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亚型
- IgG
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应用备注
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- GZMB (Granzyme B (GZMB))
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别名
- Granzyme B
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背景
- Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
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基因ID
- 3002
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NCBI登录号
- NP_004122
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UniProt
- P10144
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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