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Recombinant GZMB 抗体 (AA 19-247)

This anti-GZMB antibody is a 兔 单克隆 antibody detecting GZMB in WB, IHC, ICC, IF (p) 和 mIF. Suitable for 人.
产品编号 ABIN7449554
发货至: 中国

Quick Overview for Recombinant GZMB 抗体 (AA 19-247) (ABIN7449554)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This GZMB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

克隆位点

BLR022E
  • 抗原表位

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    AA 19-247

    原理

    Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]

    免疫原

    residues 19-247 (mature protein)

    亚型

    IgG
  • 应用备注

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B

    背景

    Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]

    基因ID

    3002

    NCBI登录号

    NP_004122

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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