Recombinant Poliovirus Receptor 抗体 (AA 28-329)
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Quick Overview for Recombinant Poliovirus Receptor 抗体 (AA 28-329) (ABIN7449549)
抗原
See all Poliovirus Receptor (PVR) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 28-329
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原理
- Rabbit anti-PVR/CD155 Recombinant Monoclonal Antibody [BLR074G]
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纯化方法
- Purified
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免疫原
- residues 28-329 (ECD)
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亚型
- IgG
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anti-Poliovirus Receptor (PVR) (AA 21-343) antibody
PVR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D2D6 unconjugated
anti-Poliovirus Receptor (PVR) (AA 22-255) antibodyPVR 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyPVR 适用: 小鼠 ELISA, FACS 宿主: 兔 Chimeric 3F1 unconjugated Recombinant Antibody
anti-Poliovirus Receptor (PVR) (AA 1-417) antibodyPVR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 56-309) antibodyPVR 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 220-345) antibodyPVR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) antibodyKD Validated PVR 适用: 人 WB 宿主: 兔 Monoclonal 23GB2575 unconjugated Recombinant Antibody
anti-Poliovirus Receptor (PVR) (Internal Region) antibodyPVR 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor (PVR) (AA 21-343) antibodyPVR 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM146 unconjugated
anti-Poliovirus Receptor (PVR) (AA 220-345) antibodyPVR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- Poliovirus Receptor (PVR)
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别名
- PVR/CD155
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背景
- PVR/CD155 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. It mediates NK cell adhesion and triggers NK cell effector functions. PVR/CD155 binds two different NK cell receptors: CD96 and CD226, and these interactions accumulate at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. PVR/Cd155 also promotes NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. PVR/CD155 also plays a role in mediating tumor cell invasion and migration. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P15151].
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基因ID
- 5817
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UniProt
- P15151
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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