CRP 抗体 (HRP)
Quick Overview for CRP 抗体 (HRP) (ABIN7449502)
抗原
See all CRP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Goat anti-Human C-Reactive Protein (CRP) Antibody HRP Conjugated
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亚型
- IgG
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应用备注
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IHC: 1:200 - 1:500
ICC: 1:200 - 1:500
WB: 1:1,000 - 1:30,000
ELISA: 1:10,000 - 1:100,000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.05 % Pro-Clean 400
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CRP (C-Reactive Protein (CRP))
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背景
- Background: The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 infection. [provided by RefSeq, Aug 2020]
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基因ID
- 1401
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UniProt
- P02741
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途径
- Carbohydrate Homeostasis
抗原
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