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CD74 抗体

This anti-CD74 antibody is a 小鼠 单克隆 antibody detecting CD74 in WB, IHC 和 ICC. Suitable for 人.
产品编号 ABIN7449435
发货至: 中国

Quick Overview for CD74 抗体 (ABIN7449435)

抗原

See all CD74 抗体
CD74 (HLA-DR-gamma (CD74))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD74 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

LN2
  • 原理

    Mouse anti-CD74 Monoclonal Antibody, Purified [LN2]

    免疫原

    human SU-DHL-4 lymphoma cells

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CD74 (HLA-DR-gamma (CD74))

    别名

    CD74

    背景

    Background: CD74 plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 also serves as cell surface receptor for the cytokine MIF. [taken from the Universal Protein Resource (UniProt) P04233].

    基因ID

    972

    NCBI登录号

    NP_001020330

    UniProt

    P04233

    途径

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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