CD74 抗体
Quick Overview for CD74 抗体 (ABIN7449435)
抗原
See all CD74 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti-CD74 Monoclonal Antibody, Purified [LN2]
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免疫原
- human SU-DHL-4 lymphoma cells
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亚型
- IgG
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应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CD74 (HLA-DR-gamma (CD74))
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别名
- CD74
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背景
- Background: CD74 plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 also serves as cell surface receptor for the cytokine MIF. [taken from the Universal Protein Resource (UniProt) P04233].
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基因ID
- 972
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NCBI登录号
- NP_001020330
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UniProt
- P04233
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途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
抗原
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