RAD17 抗体 (pSer645)
Quick Overview for RAD17 抗体 (pSer645) (ABIN7449387)
抗原
See all RAD17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer645
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原理
- Rabbit anti-Phospho Rad17 (S645) Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- surrounding serine 645
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RAD17
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别名
- Rad17
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背景
- Background: Rad17 is a cell cycle checkpoint protein that associates with the RFC complex to recruit the 9-1-1 complex (Rad9, Hus1, Rad1) to sites of DNA damage. At DNA lesions, Rad17 and RFC aid in the activation of Chk2 by ATM and ATRIP to trigger the checkpoint signaling cascade for G2 arrest.
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基因ID
- 5884
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NCBI登录号
- NP_002864
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UniProt
- O75943
抗原
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