RPS6KB1 抗体 (C-Term)
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Quick Overview for RPS6KB1 抗体 (C-Term) (ABIN7449265)
抗原
See all RPS6KB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-p70S6K Antibody, Affinity Purified
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预测反应
- Rat,Bovine,Rabbit
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纯化方法
- Affinity Purified
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免疫原
- between AA 475 and C-term
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亚型
- IgG
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应用备注
- 1:2,500 - 1:20,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
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别名
- p70S6K
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背景
- Background: 70 kDa ribosomal protein S6 kinase I (p70S6K) encodes a member of the ribosomal S6 kinase family that phosphorylates the 40 S ribosomal subunit protein S6 and eukaryotic translation initiation factor 4B (eIF4B). p70S6 functions in the PI3K and mTOR pathway to induce protein synthesis and cell growth and proliferation in response to growth factors. S6K2 is an isoform of p70S6K.
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基因ID
- 6198
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NCBI登录号
- NP_003152
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UniProt
- P23443
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect
抗原
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