FLG2 抗体 (AA 100-150)
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北京 101111
Quick Overview for FLG2 抗体 (AA 100-150) (ABIN7449193)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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原理
- Rabbit anti-FLG2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 100 and 150
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亚型
- IgG
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应用备注
- 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FLG2 (Filaggrin Family Member 2 (FLG2))
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别名
- FLG2
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背景
- Background: The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015] [taken from NCBI Entrez Gene (Gene ID: 388698)].
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基因ID
- 388698
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UniProt
- Q5D862
抗原
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