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DIS3L2 抗体 (AA 475-525)

This 兔 多克隆 antibody specifically detects DIS3L2 in WB. It exhibits reactivity toward 人.
产品编号 ABIN7449190
发货至: 中国
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Quick Overview for DIS3L2 抗体 (AA 475-525) (ABIN7449190)

抗原

See all DIS3L2 抗体
DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

适用

  • 36
  • 20
  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 27
  • 9
  • 1

克隆类型

  • 29
  • 8
多克隆

标记

  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This DIS3L2 antibody is un-conjugated

应用范围

  • 25
  • 13
  • 7
  • 6
  • 6
  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 475-525

    原理

    Rabbit anti-DIS3L2 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 475 and 525

    亚型

    IgG
  • 应用备注

    1:10,000 - 1:25,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

    别名

    DIS3L2

    背景

    Background: DIS3L2 is a 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. [taken from the Universal Protein Resource (UniProt) Q8IYB7].

    基因ID

    129563

    UniProt

    Q8IYB7

    途径

    Stem Cell Maintenance
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