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KIF20B 抗体 (AA 825-875)

This 兔 多克隆 anti-KIF20B antibody specifically detects KIF20B in IP. The antibody is reactive with 人 samples.
产品编号 ABIN7449101
发货至: 中国
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Quick Overview for KIF20B 抗体 (AA 825-875) (ABIN7449101)

抗原

See all KIF20B 抗体
KIF20B (Kinesin Family Member 20B (KIF20B))

适用

  • 16
  • 2
  • 1

宿主

  • 15
  • 1

克隆类型

  • 16
多克隆

标记

  • 10
  • 2
  • 2
  • 2
This KIF20B antibody is un-conjugated

应用范围

  • 13
  • 8
  • 3
  • 2
  • 1
  • 1
Immunoprecipitation (IP)
  • 抗原表位

    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 825-875

    原理

    Rabbit anti-KIF20B Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 825 and 875

    亚型

    IgG
  • 应用备注

    8 - 15 μL/mg lysate

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    KIF20B (Kinesin Family Member 20B (KIF20B))

    别名

    KIF20B

    背景

    Background: Kinesin family member 20B (KIF20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). KIF20B is required for proper midbody organization and abscission in polarized cortical stem cells. It plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. KIF20B participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, KIF20B cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. It is involved in cerebral cortex growth (By similarity). KIF20B acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [taken from the Universal Protein Resource (UniProt) Q96Q89].

    基因ID

    9585

    UniProt

    Q96Q89

    途径

    M Phase
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