KIF20B 抗体 (AA 825-875)
Quick Overview for KIF20B 抗体 (AA 825-875) (ABIN7449101)
抗原
See all KIF20B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 825-875
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原理
- Rabbit anti-KIF20B Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 825 and 875
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亚型
- IgG
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anti-Kinesin Family Member 20B (KIF20B) (N-Term) antibody
KIF20B 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 20B (KIF20B) (Internal Region) antibodyKIF20B 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 20B (KIF20B) (AA 1671-1780) antibodyKIF20B 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kinesin Family Member 20B (KIF20B) (AA 1200-1500) antibodyKIF20B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- 8 - 15 μL/mg lysate
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- KIF20B (Kinesin Family Member 20B (KIF20B))
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别名
- KIF20B
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背景
- Background: Kinesin family member 20B (KIF20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). KIF20B is required for proper midbody organization and abscission in polarized cortical stem cells. It plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. KIF20B participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, KIF20B cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. It is involved in cerebral cortex growth (By similarity). KIF20B acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [taken from the Universal Protein Resource (UniProt) Q96Q89].
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基因ID
- 9585
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UniProt
- Q96Q89
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途径
- M Phase
抗原
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