Recombinant CD68 抗体
Quick Overview for Recombinant CD68 抗体 (ABIN7449045)
抗原
See all CD68 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Mouse anti-CD68 Recombinant Monoclonal Antibody, Purified [KP-1]
-
纯化方法
- Purified
-
免疫原
- Lysosomal fraction of human lung macrophages
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
-
限制
- 仅限研究用
-
-
-
浓度
- 50 μg/mL
-
缓冲液
- Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- CD68 (CD68 Molecule (CD68))
-
别名
- CD68
-
背景
- Background: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].
-
基因ID
- 968
-
NCBI登录号
- NP_001242
-
UniProt
- P34810
抗原
-