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RAD9A 抗体 (C-Term)

This anti-RAD9A antibody is a 兔 多克隆 antibody detecting RAD9A in IHC 和 IF (p). Suitable for 人.
产品编号 ABIN7449007
发货至: 中国

Quick Overview for RAD9A 抗体 (C-Term) (ABIN7449007)

抗原

See all RAD9A 抗体
RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

适用

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宿主

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克隆类型

  • 140
  • 9
多克隆

标记

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This RAD9A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    C-Term

    原理

    Rabbit anti-Rad9 IHC Antibody, Affinity Purified

    预测反应

    Bovine,Dog,Pig,Panda,Monkey,Gorilla,Crab-eating macaque,Small-eared galago,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset,Ferret

    纯化方法

    Affinity Purified

    免疫原

    Between AA 350 and C-term

    亚型

    IgG
  • 应用备注

    IHC-IF: 1:50 - 1:500

    IHC: 1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    250 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

    别名

    Rad9

    背景

    Background: Rad9 is a cell-cycle checkpoint protein with 3'-5' exonuclease activity and is part of the 9-1-1 complex. The 9-1-1 complex, also called the checkpoint clamp, is a trimeric complex that includes Rad9, Hus1, and Rad1. This complex is recruited by the RAD17/RFC clamp loader to DNA lesions where it aids in the activation of Chk2 by ATM and ATRIP and the subsequent triggering of the checkpoint signaling cascade. In addition to its role in sensing DNA damage, Rad9 also functions in the base excision repair process of DNA repair.

    基因ID

    5883

    NCBI登录号

    NP_004575

    UniProt

    Q99638

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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