RAD9A 抗体 (C-Term)
Quick Overview for RAD9A 抗体 (C-Term) (ABIN7449007)
抗原
See all RAD9A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-Rad9 IHC Antibody, Affinity Purified
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预测反应
- Bovine,Dog,Pig,Panda,Monkey,Gorilla,Crab-eating macaque,Small-eared galago,Little brown bat,Northern white-cheeked gibbon,White-tufted-ear marmoset,Ferret
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纯化方法
- Affinity Purified
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免疫原
- Between AA 350 and C-term
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亚型
- IgG
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应用备注
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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别名
- Rad9
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背景
- Background: Rad9 is a cell-cycle checkpoint protein with 3'-5' exonuclease activity and is part of the 9-1-1 complex. The 9-1-1 complex, also called the checkpoint clamp, is a trimeric complex that includes Rad9, Hus1, and Rad1. This complex is recruited by the RAD17/RFC clamp loader to DNA lesions where it aids in the activation of Chk2 by ATM and ATRIP and the subsequent triggering of the checkpoint signaling cascade. In addition to its role in sensing DNA damage, Rad9 also functions in the base excision repair process of DNA repair.
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基因ID
- 5883
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NCBI登录号
- NP_004575
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UniProt
- Q99638
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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