NUMA1 抗体 (AA 900-950)
Quick Overview for NUMA1 抗体 (AA 900-950) (ABIN7448994)
抗原
See all NUMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 900-950
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原理
- Rabbit anti-NUMA IHC Antibody, Affinity Purified
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预测反应
- Gorilla,Chimpanzee,Northern white-cheeked gibbon
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纯化方法
- Affinity Purified
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免疫原
- Between AA 900 and 950
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亚型
- IgG
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应用备注
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IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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别名
- NUMA
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背景
- Background: The nuclear mitotic apparatus protein (NuMA) is a critical component of the mitotic spindle that is responsible for organizing minus-ends of microtubules at spindle poles. NUMA is regulated by phosphorylation and associates with dynein and dynactin in its phosphorylated form. Dephosphorylation of NUMA in anaphase results in the release from dynein and dynactin to allow spindle disassembly. NUMA, in association with dynein and dynactin, also interacts with 4.1R in a complex of spindle pole organizing proteins. Other NUMA interacting proteins include GAS41, tankyrase, and Rae1. These interactions indicate a broader role for NUMA function in the nucleus.
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基因ID
- 4926
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NCBI登录号
- NP_006176
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UniProt
- Q14980
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
抗原
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