Topo IIalpha (C-Term) 抗体
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北京 101111
Quick Overview for Topo IIalpha (C-Term) 抗体 (ABIN7448837)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-Topo II Alpha IHC Antibody, Affinity Purified
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预测反应
- Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Northern white-cheeked gibbon
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1500 and C-term
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亚型
- IgG
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Topo IIalpha
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别名
- Topo II Alpha
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背景
- Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
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基因ID
- 7153
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NCBI登录号
- NP_001058
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UniProt
- P11388
抗原
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