Rad6 (N-Term) 抗体
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北京 101111
Quick Overview for Rad6 (N-Term) 抗体 (ABIN7448752)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Rabbit anti-Rad6 IHC Antibody, Affinity Purified
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预测反应
- Rat,D. melanogaster,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Atlantic salmon,Tasmanian devil,Rainbow smelt,Rainbow trout,Nile tilapia,Ferret,Yeast_237561,Killifish,African elephant,Medaka fish,Thirteen-lined ground squirrel,Yeast_284593,Zebra finch,Little brown bat,Teleostei,Small-eared galago,Japanese pufferfish,Naked mole rat,Green anole,Northern white-cheeked gibbon,Sablefish,Red sea bream,Northern pike,West Indian ocean coelacanth,Baker's yeast_559292,Spotted green pufferfish,Three-spined stickleback,Yeast_284811,Yeast_284590
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纯化方法
- Affinity Purified
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免疫原
- N-terminus
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亚型
- IgG
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Rad6
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背景
- Background: Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.
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基因ID
- 7319
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NCBI登录号
- NP_003327
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UniProt
- P49459
抗原
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