Prohibitin 抗体 (AA 222-272)
Quick Overview for Prohibitin 抗体 (AA 222-272) (ABIN7448745)
抗原
See all Prohibitin (PHB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 222-272
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原理
- Rabbit anti-Prohibitin IHC Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine,Dog,Rabbit,Guinea pig_10141,Pig,Panda,Cat,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Naked mole rat,Gray short-tailed opossum,Little brown bat,Chinese hamster,Northern white-cheeked gibbon,Crab-eating macaque,Tasmanian devil,Thirteen-lined ground squirrel,Small-eared galago
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纯化方法
- Affinity Purified
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免疫原
- Between AA 222 and 272
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亚型
- IgG
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应用备注
- 1:100 - 1:500
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Prohibitin (PHB)
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别名
- Prohibitin
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背景
- Background: Prohibitin (PHB) has been identified as a tumor suppressor protein that can repress E2F-mediated transcription and arrest cell cycle progression. It has recently been shown to associate with members of the minichromosome maintenance complex such as MCM2, MCM5, and MCM7 and therefore is thought to impart its growth inhibitory effects via association with the replication machinery. Prohibitin is also implicated in regulating mitochondrial respiration and playing a role in aging.
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基因ID
- 5245
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NCBI登录号
- NP_002625
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UniProt
- P35232
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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