Menin 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for Menin 抗体 (C-Term) (ABIN7448666)
抗原
See all Menin (MEN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Rabbit anti-Menin IHC Antibody, Affinity Purified
-
预测反应
- Rat,Bovine,Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Dusky titi monkey,White-tufted-ear marmoset,African elephant,Olive baboon,Ferret,Chinese hamster,Small-eared galago,Northern white-cheeked gibbon,Naked mole rat,Eurasian common shrew,Little brown bat,Crab-eating macaque,Thirteen-lined ground squirrel,Greater horseshoe bat
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 575 and C-term
-
亚型
- IgG
-
-
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 392-554) antibody
MEN1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7D3E10 unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 501-615) antibodyMEN1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 219-395) antibodyMEN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (Internal Region) antibodyMEN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) antibodyKD Validated MEN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2590 unconjugated Recombinant Antibody
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-575) antibodyMEN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-575) antibodyMEN1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-615) antibodyMEN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) antibodyMEN1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 506-615) antibodyMEN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- 1:100 - 1:500
-
限制
- 仅限研究用
-
-
-
浓度
- 250 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
-
别名
- Menin
-
背景
- Background: Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternative names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.
-
基因ID
- 4221
-
NCBI登录号
- NP_000235
-
UniProt
- O00255
-
途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
-
