JAK2 抗体 (AA 1082-1132)
Quick Overview for JAK2 抗体 (AA 1082-1132) (ABIN7448611)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1082-1132
-
原理
- Rabbit anti-JAK2 IHC Antibody, Affinity Purified
-
预测反应
- Dog,Horse,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Naked mole rat,Ferret
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 1082 and 1132
-
亚型
- IgG
-
-
-
-
应用备注
- 1:100 - 1:500
-
限制
- 仅限研究用
-
-
-
浓度
- 250 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- JAK2 (Janus Kinase 2 (JAK2))
-
别名
- JAK2
-
背景
- Background: JAK2 (Janus kinase 2) was originally cloned via screening of mouse cDNA libraries with PCR generated probes representing highly conserved elements in the protein tyrosine kinase (PTK) family. JAK2, as well as JAK, was named after the Roman god, Janus, the god of gates or doors, and who is depicted as having two faces which face opposite directions. JAK kinases bear two nearly identical phosphate transferring domains and function to transduce signals from type I and type II cytokine receptors for the activation of STAT (signal transducers and activators of transcription) transcription factors.
-
基因ID
- 3717
-
NCBI登录号
- NP_004963
-
UniProt
- O60674
-
途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
-