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FKBP5 抗体 (AA 407-457)

This anti-FKBP5 antibody is a 兔 多克隆 antibody detecting FKBP5 in IHC. Suitable for 人.
产品编号 ABIN7448566
发货至: 中国
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Room 801-803
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Quick Overview for FKBP5 抗体 (AA 407-457) (ABIN7448566)

抗原

See all FKBP5 抗体
FKBP5 (FK506 Binding Protein 5 (FKBP5))

适用

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宿主

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克隆类型

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多克隆

标记

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This FKBP5 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 407-457

    原理

    Rabbit anti-FKBP5/FKBP51 IHC Antibody, Affinity Purified

    预测反应

    Orangutan,Chimpanzee,Northern white-cheeked gibbon

    纯化方法

    Affinity Purified

    免疫原

    Between AA 407 and 457

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FKBP5 (FK506 Binding Protein 5 (FKBP5))

    别名

    FKBP5/FKBP51

    背景

    Background: FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.

    基因ID

    2289

    NCBI登录号

    NP_004108

    UniProt

    Q13451
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