FKBP5 抗体 (AA 407-457)
Quick Overview for FKBP5 抗体 (AA 407-457) (ABIN7448566)
抗原
See all FKBP5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 407-457
-
原理
- Rabbit anti-FKBP5/FKBP51 IHC Antibody, Affinity Purified
-
预测反应
- Orangutan,Chimpanzee,Northern white-cheeked gibbon
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 407 and 457
-
亚型
- IgG
-
-
-
-
应用备注
- 1:100 - 1:500
-
限制
- 仅限研究用
-
-
-
浓度
- 100 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
-
别名
- FKBP5/FKBP51
-
背景
- Background: FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.
-
基因ID
- 2289
-
NCBI登录号
- NP_004108
-
UniProt
- Q13451
抗原
-