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AKAP8 抗体 (C-Term)

This anti-AKAP8 antibody is a 兔 多克隆 antibody detecting AKAP8 in IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7448405
发货至: 中国

Quick Overview for AKAP8 抗体 (C-Term) (ABIN7448405)

抗原

See all AKAP8 抗体
AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This AKAP8 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    原理

    Rabbit anti-AKAP8/AKAP95 IHC Antibody, Affinity Purified

    预测反应

    Bovine,Gorilla,Chimpanzee

    纯化方法

    Affinity Purified

    免疫原

    Between AA 642 and C-term

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

    别名

    AKAP8/AKAP95

    背景

    Background: AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus.

    基因ID

    10270

    NCBI登录号

    NP_005849

    UniProt

    O43823

    途径

    SARS-CoV-2 Protein Interactome
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