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STING/TMEM173 抗体

This anti-STING/TMEM173 antibody is a 兔 单克隆 antibody detecting STING/TMEM173 in WB 和 IHC (p). Suitable for 人 和 大鼠.
产品编号 ABIN7384500
发货至: 中国

Quick Overview for STING/TMEM173 抗体 (ABIN7384500)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

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人, 大鼠

宿主

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克隆类型

  • 77
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单克隆

标记

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This STING/TMEM173 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

R06-9A7
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000 IHC 1:50-1:100

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    Transmembrane Protein 173

    背景

    Endoplasmic reticulum IFN stimulator,Endoplasmic reticulum interferon stimulator,ERIS,FLJ38577,hMITA,hSTING,Mediator of IRF3 activation,MITA,Mitochondrial mediator of IRF3 activation,MPYS,N terminal methionine proline tyrosine serine plasma membrane tetraspanner,NET23,Stimulator of interferon genes,Stimulator of interferon genes protein,STING,TM173,Tmem173,Transmembrane protein 173,This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

    分子量

    Observed_MW: 40kDa

    Calculated_MW: 42kDa

    基因ID

    340061

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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