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MLH1 抗体

This anti-MLH1 antibody is a 兔 单克隆 antibody detecting MLH1 in WB 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7384468
发货至: 中国

Quick Overview for MLH1 抗体 (ABIN7384468)

抗原

See all MLH1 抗体
MLH1 (MutL Homolog 1 (MLH1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This MLH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

R02-2E8
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000 IF 1:50-1:100

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MLH1 (MutL Homolog 1 (MLH1))

    别名

    MLH1

    背景

    COCA 2,COCA2,DNA mismatch repair protein Mlh1,FCC 2,FCC2,hMLH 1,hMLH1,HNPCC 2,HNPCC,HNPCC2,MGC5172,MLH 1,MLH1,MLH1,MutL homolog 1 (E. coli),MutL homolog 1,MutL homolog 1 colon cancer nonpolyposis type 2,MutL homolog 1,colon cancer,nonpolyposis type 2 (E. coli),MutL protein homolog 1,MutL,E. coli,homolog of,1,This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

    分子量

    Observed_MW: 85kDa

    Calculated_MW: 85kDa

    基因ID

    4292

    UniProt

    P40692

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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