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ALIX 抗体

PDCD6IP 适用: 人, 大鼠, Hamster WB 宿主: 兔 Monoclonal R03-8C2 unconjugated
产品编号 ABIN7384341
发货至: 中国
  • 抗原 See all ALIX (PDCD6IP) 抗体
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    适用
    • 74
    • 32
    • 30
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, Hamster
    宿主
    • 64
    • 11
    • 1
    克隆类型
    • 59
    • 16
    单克隆
    标记
    • 30
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ALIX antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 26
    • 21
    • 13
    • 11
    • 11
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity Purified
    克隆位点
    R03-8C2
    亚型
    IgG
    Top Product
    Discover our top product PDCD6IP Primary Antibody
  • 应用备注
    WB 1:1000-1:2000
    限制
    仅限研究用
  • 浓度
    300 μg/mL
    缓冲液
    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
    别名
    ALIX (PDCD6IP 产品)
    背景
    PDCD6IP,AIP1,ALIX,DRIP4,HP95,This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
    分子量

    Observed_MW: 96kDa

    Calculated_MW: 96kDa

    基因ID
    10015
    UniProt
    Q8WUM4
    途径
    p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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