ALIX 抗体
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- 抗原 See all ALIX (PDCD6IP) 抗体
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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适用
- 人, 大鼠, Hamster
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This ALIX antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity Purified
- 克隆位点
- R03-8C2
- 亚型
- IgG
- Top Product
- Discover our top product PDCD6IP Primary Antibody
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- 应用备注
- WB 1:1000-1:2000
- 限制
- 仅限研究用
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- 浓度
- 300 μg/mL
- 缓冲液
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
- 别名
- ALIX (PDCD6IP 产品)
- 背景
- PDCD6IP,AIP1,ALIX,DRIP4,HP95,This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
- 分子量
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Observed_MW: 96kDa
Calculated_MW: 96kDa
- 基因ID
- 10015
- UniProt
- Q8WUM4
- 途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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