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c-MYC 抗体

This anti-c-MYC antibody is a 兔 单克隆 antibody detecting c-MYC in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7384328
发货至: 中国

Quick Overview for c-MYC 抗体 (ABIN7384328)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

R05-5E2
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    c Myc

    背景

    AU016757,Avian myelocytomatosis viral oncogene homolog,bHLHe39,c Myc,Class E basic helix-loop-helix protein 39,MRTL,Myc,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,myc-related translation/localization regulatory factor,MYC,Myc2,MYCC,Myelocytomatosis oncogene,Niard,Nird,Oncogene Myc,OTTHUMP00000158589,Proto-oncogene c-Myc,Protooncogene homologous to myelocytomatosis virus,RNCMYC,Transcription factor p64,Transcriptional regulator Myc-A,V-Myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian),This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

    分子量

    Observed_MW: 57-65kDa

    Calculated_MW: 49kDa

    基因ID

    4609

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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