c-MYC 抗体
Quick Overview for c-MYC 抗体 (ABIN7384328)
抗原
See all c-MYC (MYC) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Purified
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亚型
- IgG
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应用备注
- WB 1:1000-1:2000
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限制
- 仅限研究用
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浓度
- 300 μg/mL
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缓冲液
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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别名
- c Myc
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背景
- AU016757,Avian myelocytomatosis viral oncogene homolog,bHLHe39,c Myc,Class E basic helix-loop-helix protein 39,MRTL,Myc,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,myc-related translation/localization regulatory factor,MYC,Myc2,MYCC,Myelocytomatosis oncogene,Niard,Nird,Oncogene Myc,OTTHUMP00000158589,Proto-oncogene c-Myc,Protooncogene homologous to myelocytomatosis virus,RNCMYC,Transcription factor p64,Transcriptional regulator Myc-A,V-Myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian),This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
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分子量
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Observed_MW: 57-65kDa
Calculated_MW: 49kDa
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基因ID
- 4609
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UniProt
- P01106
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途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
抗原
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