Vimentin 抗体
Quick Overview for Vimentin 抗体 (ABIN7384323)
抗原
See all Vimentin (VIM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Affinity Purified
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亚型
 - IgG
 
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应用备注
 - WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
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限制
 - 仅限研究用
 
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浓度
 - 300 μg/mL
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缓冲液
 - 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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- Vimentin (VIM)
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别名
 - Vimentin
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背景
 - CTRCT30,Epididymis luminal protein 113,FLJ36605,HEL113,VIM,VIME,Vimentin,Vimentin,also named as VIM,belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells,especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA, 191160) and inhibited by the antiinflammatory cytokine IL10 (124092),suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
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分子量
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Observed_MW: 54kDa
Calculated_MW: 54kDa
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基因ID
 - 7431
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UniProt
 - P08670
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途径
 - Caspase Cascade in Apoptosis
 
抗原
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