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Vimentin 抗体

This anti-Vimentin antibody is a 兔 单克隆 antibody detecting Vimentin in WB, IF 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 Hamster.
产品编号 ABIN7384323
发货至: 中国

Quick Overview for Vimentin 抗体 (ABIN7384323)

抗原

See all Vimentin (VIM) 抗体
Vimentin (VIM)

适用

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人, 小鼠, 大鼠, Hamster

宿主

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克隆类型

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单克隆

标记

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This Vimentin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

R02-8C4
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Vimentin (VIM)

    别名

    Vimentin

    背景

    CTRCT30,Epididymis luminal protein 113,FLJ36605,HEL113,VIM,VIME,Vimentin,Vimentin,also named as VIM,belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells,especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA, 191160) and inhibited by the antiinflammatory cytokine IL10 (124092),suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

    分子量

    Observed_MW: 54kDa

    Calculated_MW: 54kDa

    基因ID

    7431

    UniProt

    P08670

    途径

    Caspase Cascade in Apoptosis
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