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PRMT5 抗体

This anti-PRMT5 antibody is a 兔 多克隆 antibody detecting PRMT5 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7383995
发货至: 中国

Quick Overview for PRMT5 抗体 (ABIN7383995)

抗原

See all PRMT5 抗体
PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

适用

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人, 小鼠, 大鼠

宿主

  • 82
  • 6
  • 2
  • 1

克隆类型

  • 70
  • 20
  • 1
多克隆

标记

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This PRMT5 antibody is un-conjugated

应用范围

  • 60
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Western Blotting (WB), ELISA
  • 纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human PRMT5

    亚型

    IgG
  • 应用备注

    WB 1:200-1:1000

    限制

    仅限研究用
  • 浓度

    0.3 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

    别名

    PRMT5

    背景

    72 kDa ICln binding protein,72 kDa ICln-binding protein,ANM5,Histone synthetic lethal 7,S. cerevisiae,homolog of,Histone-arginine N-methyltransferase PRMT5,HMT1 hnRNP methyltransferase like 5,HOMOLOG OF,SKB1,HRMT1L5,IBP72,Jak-binding protein 1,JBP 1,JBP1,PRMT 5,PRMT5,Protein arginine methyltransferase 5,Protein arginine N methyltransferase 5,Protein arginine N methyltransferase 5 N terminally processed,Protein arginine N-methyltransferase 5,S. POMBE,S. POMBE HOMOLOG OF,SKB1,SHK1 KINASE BINDING PROTEIN 1,Shk1 kinase binding protein 1 homolog,Shk1 kinase-binding protein 1 homolog,Shk1 kinase/binding protein 1,S. pombe,homolog of,SKB 1,SKB1,SKB1 homolog,SKB1: SKB1 homolog (S. pombe),SKB1Hs,Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation.

    分子量

    71 kDa

    NCBI登录号

    NP_001034708

    UniProt

    O14744

    途径

    Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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