GLI1 抗体 (AA 200-300)
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北京 101111
Quick Overview for GLI1 抗体 (AA 200-300) (ABIN7271533)
抗原
See all GLI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-300
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原理
- GLI1 Rabbit pAb
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序列
- EKPYMCEHEG CSKAFSNASD RAKHQNRTHS NEKPYVCKLP GCTKRYTDPS SLRKHVKTVH GPDAHVTKRH RGDGPLPRAP SISTVEPKRE REGGPIREES R
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GLI1 (NP_001153517.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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别名
- GLI1
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背景
- This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.,GLI1,GLI,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI1
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分子量
- 104kDa/113kDa/117kDa
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基因ID
- 2735
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UniProt
- P08151
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途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
抗原
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