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EZH1 抗体 (AA 471-510) (HRP)

This anti-EZH1 antibody is a 兔 多克隆 antibody detecting EZH1 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN717635
发货至: 中国

Quick Overview for EZH1 抗体 (AA 471-510) (HRP) (ABIN717635)

抗原

See all EZH1 抗体
EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

适用

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人, 小鼠, 大鼠

宿主

  • 68
  • 4
  • 1

克隆类型

  • 69
  • 4
多克隆

标记

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This EZH1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 471-510

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EZH1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

    别名

    EZH1

    背景

    Synonyms: Enhancer of zeste homolog 1Drosophila, Enhancer of zeste homolog 1, ENX-2, ENX2, EZH1, EZH1: enhancer of zeste homolog 1 Drosophila, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1, KIAA0388.

    Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.

    基因ID

    2145
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