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XIAP 抗体

This anti-XIAP antibody is a 兔 单克隆 antibody detecting XIAP in WB. Suitable for 人.
产品编号 ABIN7271400
发货至: 中国

Quick Overview for XIAP 抗体 (ABIN7271400)

抗原

See all XIAP 抗体
XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

适用

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宿主

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克隆类型

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单克隆

标记

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This XIAP antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

KO Validated
  • 原理

    [KO Validated] XIAP Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human XIAP.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

    别名

    XIAP

    背景

    This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.,XIAP,API3,BIRC4,IAP-3,ILP1,MIHA,XLP2,hIAP-3,hIAP3,Cancer,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Death receptors & ligands,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,XIAP

    分子量

    56kDa

    基因ID

    331

    UniProt

    P98170

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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