UPF3A 抗体 (AA 327-476)
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北京 101111
Quick Overview for UPF3A 抗体 (AA 327-476) (ABIN7271227)
抗原
See all UPF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 327-476
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原理
- UPF3A Rabbit pAb
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序列
- EGSLEEPQET SHSGSDKEHR DVERSQEQES EAQRYHVDDG RRHRAHHEPE RLSRRSEDEQ RWGKGPGQDR GKKGSQDSGA PGEAMERLGR AQRCDDSPAP RKERLANKDR PALQLYDPGA RFRARECGGN RRICKAEGSG TGPEKREEAE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 327-476 of human UPF3A (NP_075387.1).
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亚型
- IgG
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anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 274-374) antibody
UPF3A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 1-443) antibodyUPF3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 382-475) antibodyUPF3A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 359-408) antibodyUPF3A 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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别名
- UPF3A
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背景
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene.,UPF3A,HUPF3A,RENT3A,UPF3,Epigenetics & Nuclear Signaling,Signal Transduction,UPF3A
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分子量
- 17kDa/51kDa/54kDa
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基因ID
- 65110
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UniProt
- Q9H1J1
抗原
-
