UGT1A6 抗体 (AA 65-270)
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Quick Overview for UGT1A6 抗体 (AA 65-270) (ABIN7271193)
抗原
See all UGT1A6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-270
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原理
- UGT1A6 Rabbit pAb
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序列
- LLLKESKYYT RKIYPVPYDQ EELKNRYQSF GNNHFAERSF LTAPQTEYRN NMIVIGLYFI NCQSLLQDRD TLNFFKESKF DALFTDPALP CGVILAEYLG LPSVYLFRGF PCSLEHTFSR SPDPVSYIPR CYTKFSDHMT FSQRVANFLV NLLEPYLFYC LFSKYEELAS AVLKRDVDII TLYQKVSVWL LRYDFVLEYP RPVMPN
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
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别名
- UGT1A6
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背景
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.,UGT1A6;GNT1;HLUGP;HLUGP1;UDPGT;UDPGT 1-6;UGT1;UGT1A6S;UGT1F;UDPGT1-6,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A6
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分子量
- 29kDa/50kDa/60kDa
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基因ID
- 54578
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UniProt
- P19224
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
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