TYROBP 抗体 (C-Term)
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Quick Overview for TYROBP 抗体 (C-Term) (ABIN7271115)
抗原
See all TYROBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TYROBP Rabbit pAb
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序列
- DLVLTVLIAL AVYFLGRLVP RGRGAAEAAT RKQRITETES PYQELQGQRS DVYSDLNTQR PYYK
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TYROBP (NP_003323.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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别名
- TYROBP
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背景
- This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.,TYROBP,DAP12,KARAP,PLOSL,Signal Transduction,TYROBP
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分子量
- 11kDa/12kDa
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基因ID
- 7305
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UniProt
- O43914
抗原
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