Translin 抗体 (AA 50-150)
Quick Overview for Translin 抗体 (AA 50-150) (ABIN7270923)
抗原
See all Translin (TSN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-150
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原理
- TSN Rabbit pAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Translin (TSN)
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别名
- TSN
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背景
- This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.,BCLF-1,C3PO,RCHF1,REHF-1,TBRBP,TRSLN,TSN,translin,DNA Damage & Repair,Epigenetics & Nuclear Signaling,TSN
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分子量
- 17kDa/26kDa
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基因ID
- 7247
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UniProt
- Q15631
抗原
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