TBL1X 抗体 (AA 100-200)
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北京 101111
Quick Overview for TBL1X 抗体 (AA 100-200) (ABIN7270901)
抗原
See all TBL1X 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-200
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原理
- TBL1X Rabbit pAb
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序列
- LISILQKGLQ YVEAEISINE DGTVFDGRPI ESLSLIDAVM PDVVQTRQQA FREKLAQQQA SAAAAAAAAT AAATAATTTS AGVSHQNPSK NREATVNGEE N
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TBL1X (NP_005638.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
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别名
- TBL1X
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背景
- The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.,TBL1X,EBI,SMAP55,TBL1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,TBL1X
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分子量
- 57kDa/62kDa
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基因ID
- 6907
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UniProt
- O60907
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途径
- Sensory Perception of Sound, Regulation of Lipid Metabolism by PPARalpha
抗原
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