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TLR9 抗体 (AA 350-450)

This anti-TLR9 antibody is a 兔 多克隆 antibody detecting TLR9 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7270849
发货至: 中国

Quick Overview for TLR9 抗体 (AA 350-450) (ABIN7270849)

抗原

See all TLR9 抗体
TLR9 (Toll-Like Receptor 9 (TLR9))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 350-450

    原理

    TLR9 Rabbit pAb

    序列

    SFAHLSLAPS FGSLVALKEL DMHGIFFRSL DETTLRPLAR LPMLQTLRLQ MNFINQAQLG IFRAFPGLRY VDLSDNRISG ASELTATMGE ADGGEKVWLQ P

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TLR9 (NP_059138.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TLR9 (Toll-Like Receptor 9 (TLR9))

    别名

    TLR9

    背景

    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.,TLR9,CD289,Signal Transduction,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR9

    分子量

    109kDa/114kDa/115kDa/118kDa

    基因ID

    54106

    UniProt

    Q9NR96

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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