TLR6 抗体 (AA 32-200)
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北京 101111
Quick Overview for TLR6 抗体 (AA 32-200) (ABIN7270847)
抗原
See all TLR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-200
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原理
- TLR6 Rabbit pAb
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序列
- NEFAVDKSKR GLIHVPKDLP LKTKVLDMSQ NYIAELQVSD MSFLSELTVL RLSHNRIQLL DLSVFKFNQD LEYLDLSHNQ LQKISCHPIV SFRHLDLSFN DFKALPICKE FGNLSQLNFL GLSAMKLQKL DLLPIAHLHL SYILLDLRNY YIKENETESL QILNAKTLH
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 32-200 of human TLR6 (NP_006059.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TLR6 (Toll-Like Receptor 6 (TLR6))
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别名
- TLR6
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背景
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.,TLR6,CD286,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TLR6
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分子量
- 55kDa/91kDa
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基因ID
- 10333
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UniProt
- Q9Y2C9
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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