TBK1 抗体 (pSer172)
Quick Overview for TBK1 抗体 (pSer172) (ABIN7270721)
抗原
See all TBK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer172
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原理
- Phospho-TBK1/NAK-S172 Rabbit mAb
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交叉反应
- 人, 小鼠
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding S172 of human TBK1/NAK
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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别名
- TBK1
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背景
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],FTDALS4, NAK, T2K,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,NF-kB Signaling Pathway,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Kinase of Akt,Protein phosphorylation,Signal Transduction,Toll-like Receptor Signaling Pathway,TBK1
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分子量
- 84kDa
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基因ID
- 29110
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UniProt
- Q9UHD2
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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