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SF3B1 抗体 (AA 1-144)

This anti-SF3B1 antibody is a 兔 多克隆 antibody detecting SF3B1 in WB 和 IF. Suitable for 人.
产品编号 ABIN7270543
发货至: 中国

Quick Overview for SF3B1 抗体 (AA 1-144) (ABIN7270543)

抗原

See all SF3B1 抗体
SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

适用

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宿主

  • 57
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克隆类型

  • 42
  • 19
多克隆

标记

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This SF3B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    • 2
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    • 1
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    AA 1-144

    原理

    SF3B1 Rabbit pAb

    序列

    MAKIAKTHED IEAQIREIQG KKAALDEAQG VGLDSTGYYD QEIYGGSDSR FAGYVTSIAA TELEDDDDDY SSSTSLLGQK KPGYHAPVAL LNDIPQSTEQ YDPFAEHRPP KIADREDEYK KHRRTMIISP ERLDPFADGF YSAA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SF3B1 (NP_001005526.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    别名

    SF3B1

    背景

    This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.,SF3B1,Hsh155,MDS,PRP10,PRPF10,SAP155,SF3b155,Epigenetics & Nuclear Signaling,RNA Binding,SF3B1

    分子量

    16kDa/145kDa

    基因ID

    23451

    UniProt

    O75533

    途径

    Chromatin Binding
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