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SF3B1 抗体 (pThr313)

This anti-SF3B1 antibody is a 兔 多克隆 antibody detecting SF3B1 in WB. Suitable for 人.
产品编号 ABIN7270541
发货至: 中国

Quick Overview for SF3B1 抗体 (pThr313) (ABIN7270541)

抗原

See all SF3B1 抗体
SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

适用

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宿主

  • 57
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克隆类型

  • 42
  • 19
多克隆

标记

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This SF3B1 antibody is un-conjugated

应用范围

  • 48
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Western Blotting (WB)
  • 抗原表位

    • 15
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    pThr313

    原理

    Phospho-SF3B1-T313 Rabbit pAb

    序列

    AETPR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around T313 of human SF3B1 (NP_036565.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    别名

    SF3B1

    背景

    This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.,SF3B1,Hsh155,MDS,PRP10,PRPF10,SAP155,SF3b155,Epigenetics & Nuclear Signaling,RNA Binding,Protein phosphorylation,SF3B1

    分子量

    16kDa/145kDa

    基因ID

    23451

    UniProt

    O75533

    途径

    Chromatin Binding
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