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Selenoprotein S 抗体 (AA 50-150)

This anti-Selenoprotein S antibody is a 兔 多克隆 antibody detecting Selenoprotein S in WB. Suitable for 人.
产品编号 ABIN7270197
发货至: 中国

Quick Overview for Selenoprotein S 抗体 (AA 50-150) (ABIN7270197)

抗原

See all Selenoprotein S (SELS) 抗体
Selenoprotein S (SELS)

适用

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宿主

  • 15
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克隆类型

  • 18
  • 3
多克隆

标记

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This Selenoprotein S antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 7
    • 1
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    AA 50-150

    原理

    VIMP Rabbit pAb

    序列

    KLSARLRALR QRQLDRAAAA VEPDVVVKRQ EALAAARLKM QEELNAQVEK HKEKLKQLEE EKRRQKIEMW DSMQEGKSYK GNAKKPQEED SPGPSTSSVL K

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human VIMP (NP_982298.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Selenoprotein S (SELS)

    别名

    SELENOS

    背景

    This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR have been shown to function as modulators of Sec insertion in this protein (PMID:23614019). An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene.,SELENOS,AD-015,ADO15,SBBI8,SELS,SEPS1,VIMP,Signal Transduction,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,SELENOS

    分子量

    21kDa

    基因ID

    55829

    UniProt

    Q9BQE4

    途径

    Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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