Selenoprotein S 抗体 (Middle Region)
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北京 101111
Quick Overview for Selenoprotein S 抗体 (Middle Region) (ABIN2783218)
抗原
See all Selenoprotein S (SELS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- SELENOS Antibody - middle region
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序列
- PDVVVKRQEA LAAARLKMQE ELNAQVEKHK EKLKQLEEEK RRQKIEMWDS
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预测反应
- Cow: 93%, Dog: 86%, Goat: 75%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Yeast: 90%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SELS. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SELS
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anti-Selenoprotein S (SELS) (AA 1-187) antibody
SELS 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7F8G1 unconjugated
anti-Selenoprotein S (SELS) (AA 1-187) antibodySELS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5G4A10 unconjugated
anti-Selenoprotein S (SELS) (AA 1-187) antibodySELS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Selenoprotein S (SELS) (AA 72-121) antibodySELS 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Selenoprotein S (SELS) (AA 1-187) antibodySELS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Selenoprotein S (SELS) antibodySELS 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selenoprotein S (SELS) (AA 125-175) antibodySELS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48082-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Influence of SelS gene silence on beta-Mercaptoethanol-mediated endoplasmic reticulum stress and cell apoptosis in HepG2 cells." in: Biochimica et biophysica acta, Vol. 1800, Issue 5, pp. 511-7, (2010) (PubMed).
: "Genetic association of preeclampsia to the inflammatory response gene SEPS1." in: American journal of obstetrics and gynecology, Vol. 198, Issue 3, pp. 336.e1-5, (2008) (PubMed).
: "Role of SelS in lipopolysaccharide-induced inflammatory response in hepatoma HepG2 cells." in: Archives of biochemistry and biophysics, Vol. 478, Issue 1, pp. 1-6, (2008) (PubMed).
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- Selenoprotein S (SELS)
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别名
- SELENOS
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背景
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Background Information: This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion. An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene (PMID:23614019).
Gene Name: selenoprotein S
Alternative Symbols: SELS, VIMP, ADO15, SBBI8, SEPS1, AD-015
Protein Name: selenoprotein S
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分子量
- 21kDa
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基因ID
- 55829
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NCBI登录号
- NP_060915
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UniProt
- Q9BQE4
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途径
- Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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