SKP1 抗体
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北京 101111
Quick Overview for SKP1 抗体 (ABIN7270120)
抗原
See all SKP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SKP1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human SKP1
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
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别名
- SKP1
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背景
- This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008],EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centromere,Cell Cycle_Centrosome,Kinase,Signal Transduction,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,SKP1
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分子量
- 19kDa
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基因ID
- 6500
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UniProt
- P63208
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
抗原
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