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RNF20 抗体 (AA 1-260)

This anti-RNF20 antibody is a 兔 多克隆 antibody detecting RNF20 in WB. Suitable for 人.
产品编号 ABIN7270072
发货至: 中国

Quick Overview for RNF20 抗体 (AA 1-260) (ABIN7270072)

抗原

See all RNF20 抗体
RNF20 (Ring Finger Protein 20 (RNF20))

适用

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宿主

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克隆类型

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多克隆

标记

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This RNF20 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-260

    原理

    RNF20 Rabbit pAb

    序列

    MSGIGNKRAA GEPGTSMPPE KKAAVEDSGT TVETIKLGGV SSTEELDIRT LQTKNRKLAE MLDQRQAIED ELREHIEKLE RRQATDDASL LIVNRYWSQF DENIRIILKR YDLEQGLGDL LTERKALVVP EPEPDSDSNQ ERKDDRERGE GQEPAFSFLA TLASSSSEEM ESQLQERVES SRRAVSQIVT VYDKLQEKVE LLSRKLNSGD NLIVEEAVQE LNSFLAQENM RLQELTDLLQ EKHRTMSQEF SKLQSKVETA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNF20 (NP_062538.5).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RNF20 (Ring Finger Protein 20 (RNF20))

    别名

    RNF20

    背景

    The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).,RNF20,BRE1,BRE1A,hBRE1,Epigenetics & Nuclear Signaling,Histones,Chromatin Modifying Enzymes,Ubiquitination,Cell Biology & Developmental Biology,Ubiquitin,RNF20

    分子量

    113kDa

    基因ID

    56254

    UniProt

    Q5VTR2
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