GRF2 抗体 (AA 844-1095)
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Quick Overview for GRF2 抗体 (AA 844-1095) (ABIN7269849)
抗原
See all GRF2 (RAPGEF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 844-1095
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原理
- RAPGEF1 Rabbit pAb
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序列
- ARGVAARPGT LHDFHSHEIA EQLTLLDAEL FYKIEIPEVL LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK IMKHLRKLNN FNSYLAILSA LDSAPIRRLE WQKQTSEGLA EYCTLIDSSS SFRAYRAALS EVEPPCIPYL GLILQDLTFV HLGNPDYIDG KVNFSKRWQQ FNILDSMRCF QQAHYDMRRN DDIINFFNDF SDHLAEEALW ELSLKIKPRN ITRRKTDREE KT
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 844-1095 of human RAPGEF1 (NP_941372.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
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别名
- RAPGEF1
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背景
- This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.,RAPGEF1,C3G,GRF2,Signal Transduction,G protein signaling,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,RAPGEF1
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分子量
- 116kDa/120kDa/122kDa
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基因ID
- 2889
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UniProt
- Q13905
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途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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