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GRF2 抗体 (C-Term)

The 兔 多克隆 anti-GRF2 antibody is suitable to detect GRF2 in samples from 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 斑马鱼. It has been validated for WB.
产品编号 ABIN2785868
发货至: 中国
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Quick Overview for GRF2 抗体 (C-Term) (ABIN2785868)

抗原

See all GRF2 (RAPGEF1) 抗体
GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼

宿主

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兔

克隆类型

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多克隆

标记

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This GRF2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    RAPGEF1 Antibody - C-terminal region

    序列

    LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against RAPGEF1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human RAPGEF1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54753-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

    别名

    RAPGEF1

    背景

    Background Information: RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

    Gene Name: Rap guanine nucleotide exchange factor (GEF) 1

    Alternative Symbols: C3G, GRF2

    Protein Name: Rap guanine nucleotide exchange factor 1

    分子量

    120kDa

    基因ID

    2889

    NCBI登录号

    NP_005303

    UniProt

    Q13905

    途径

    Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
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