RSAD2 抗体 (AA 42-361)
Our Local Distributor
北京 101111
Quick Overview for RSAD2 抗体 (AA 42-361) (ABIN7269832)
抗原
See all RSAD2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 42-361
-
原理
- RSAD2 Rabbit pAb
-
序列
- LATKRRKQQL VLRGPDETKE EEEDPPLPTT PTSVNYHFTR QCNYKCGFCF HTAKTSFVLP LEEAKRGLLL LKEAGMEKIN FSGGEPFLQD RGEYLGKLVR FCKVELRLPS VSIVSNGSLI RERWFQNYGE YLDILAISCD SFDEEVNVLI GRGQGKKNHV ENLQKLRRWC RDYRVAFKIN SVINRFNVEE DMTEQIKALN PVRWKVFQCL LIEGENCGED ALREAERFVI GDEEFERFLE RHKEVSCLVP ESNQKMKDSY LILDEYMRFL NCRKGRKDPS KSILDVGVEE AIKFSGFDEK MFLKRGGKYI WSKADLKLDW
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 42-361 of human RSAD2 (NP_542388.2).
-
亚型
- IgG
-
-
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibody
RSAD2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 262-361) antibodyRSAD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, Cow, 兔, Pig, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (N-Term) antibodyRSAD2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 1-361) antibodyRSAD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 101-150) antibodyRSAD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
-
别名
- RSAD2
-
背景
- Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV, hepatitis C virus (HCV, west Nile virus (WNV, dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV, zika virus, and human immunodeficiency virus (HIV-1. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR-mediated GATA3 activation and optimal T-helper 2 (Th2 cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.,RSAD2,2510004L01Rik,cig33,cig5,vig1,Immunology & Inflammation,RSAD2
-
分子量
- 42kDa
-
基因ID
- 91543
-
UniProt
- Q8WXG1
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
-
