(1 reference)-
- 抗原 See all RSAD2 抗体
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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适用
- 小鼠
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宿主
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Human
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克隆类型
- 单克隆
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标记
- This RSAD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- 过滤
- 0.2 μm filtered
- 克隆位点
- MaP-VIP
- Top Product
- Discover our top product RSAD2 Primary Antibody
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anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibody
RSAD2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 262-361) antibodyRSAD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, Cow, 兔, Pig, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibodyRSAD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (N-Term) antibodyRSAD2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 1-361) antibodyRSAD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 101-150) antibodyRSAD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, Pig, 豚鼠, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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: "Innate immune recognition triggers secretion of lysosomal enzymes by macrophages." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 9, pp. 1179-89, (2007) (PubMed).
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: "Innate immune recognition triggers secretion of lysosomal enzymes by macrophages." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 9, pp. 1179-89, (2007) (PubMed).
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- 抗原
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
- 别名
- Viperin (RSAD2 产品)
- 别名
- CIG6 antibody, RSAD2 antibody, 2510004L01Rik antibody, cig33 antibody, cig5 antibody, vig1 antibody, Vig1 antibody, Best5 antibody, si:ch211-276e8.2 antibody, zgc:112342 antibody, viperin antibody, rsad2 antibody, radical S-adenosyl methionine domain containing 2 antibody, viperin antibody, RSAD2 antibody, Rsad2 antibody, rsad2 antibody, vig1 antibody
- 背景
- The monoclonal antibody MaP.VIP recognizes mouse Viperin, a 42 kDa protein belonging to the RSAD2 family. Viperin is the abbreviation of Virus inhibitory protein endoplasmic reticulum-associated interferon-inducible. It is an evolutionary conserved protein that is highly inducible by both type I and type II interferons. However, little or no induction by interferon gamma is observed in monocytic cell lines. Infection by many viruses, including human cytomegalovirus (hCMV), hepatitis C virus, yellow fever virus and Sendai virus, strongly induces viperin expression, suggesting a role in the host antiviral response. Viperin has also been shown to be important for the host anti-HIV responses. Furthermore, expression of viperin inhibits influenza replication by perturbing its release from the plasma membrane. Viperin expression alters plasma membrane fluidity by affecting formation of lipid rafts which are detergent-resistant membrane microdomains known to be the sites of influenza virus budding. HCMV infection induces the redistribution of viperin from the endoplasmic reticulum to the Golgi complex and ultimately to cytoplasmic vacuoles, suggesting that viperin may function at a distinct level in the viral lifecycle, at the point of glycosylated viral protein transport. Radical S-adenosine methionine domain-containing protein 2, Virus inhibitory protein endoplasmic Aliases reticulum-associated interferon-inducible, Cytomegalovirus-induced gene 5 protein, Cig5 Recombinant mouse viperin fragment (residues 92-362) Immunogen Mouse IgG2a
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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