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RAB8A 抗体 (AA 1-207)

This anti-RAB8A antibody is a 兔 多克隆 antibody detecting RAB8A in IF. Suitable for 人.
产品编号 ABIN7269815
发货至: 中国

Quick Overview for RAB8A 抗体 (AA 1-207) (ABIN7269815)

抗原

See all RAB8A 抗体
RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAB8A antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
  • 抗原表位

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    AA 1-207

    原理

    RAB8A Rabbit pAb

    序列

    MAKTYDYLFK LLLIGDSGVG KTCVLFRFSE DAFNSTFIST IGIDFKIRTI ELDGKRIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIR NWIRNIEEHA SADVEKMILG NKCDVNDKRQ VSKERGEKLA LDYGIKFMET SAKANINVEN AFFTLARDIK AKMDKKLEGN SPQGSNQGVK ITPDQQKRSS FFRCVLL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human RAB8A (NP_005361.2).

    亚型

    IgG
  • 应用备注

    IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

    别名

    RAB8A

    背景

    The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.,RAB8A,MEL,RAB8,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,RAB8A

    分子量

    23kDa

    基因ID

    4218

    UniProt

    P61006

    途径

    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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