POGLUT1 抗体 (AA 160-280)
Our Local Distributor
北京 101111
Quick Overview for POGLUT1 抗体 (AA 160-280) (ABIN7269673)
抗原
See all POGLUT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 160-280
-
原理
- POGLUT1 Rabbit pAb
-
序列
- MYPAWTFWEG GPAVWPIYPT GLGRWDLFRE DLVRSAAQWP WKKKNSTAYF RGSRTSPERD PLILLSRKNP KLVDAEYTKN QAWKSMKDTL GKPAAKDVHL VDHCKYKYLF NFRGVAASFR F
-
交叉反应
- 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
-
别名
- POGLUT1
-
背景
- This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],C3orf9,CLP46,KDELCL1,KTELC1,LGMD2Z,MDS010,MDSRP,Rumi,hCLP46,POGLUT1,Cell Biology & Developmental Biology,POGLUT1
-
基因ID
- 56983
-
UniProt
- Q8NBL1
-
途径
- Notch Signaling
抗原
-