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PNN 抗体 (AA 1-100)

This anti-PNN antibody is a 兔 多克隆 antibody detecting PNN in WB. Suitable for 人.
产品编号 ABIN7269378
发货至: 中国

Quick Overview for PNN 抗体 (AA 1-100) (ABIN7269378)

抗原

See all PNN 抗体
PNN (Pinin, Desmosome Associated Protein (PNN))

适用

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宿主

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克隆类型

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多克隆

标记

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This PNN antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-100

    原理

    PNN Rabbit pAb

    序列

    MAVAVRTLQE QLEKAKESLK NVDENIRKLT GRDPNDVRPI QARLLALSGP GGGRGRGSLL LRRGFSDSGG GPPAKQRDLE GAVSRLGGER RTRRESRQES

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PNN (NP_002678.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PNN (Pinin, Desmosome Associated Protein (PNN))

    别名

    PNN

    背景

    Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.,PNN,DRS,DRSP,SDK3,memA,pinin,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,Tumor suppressors,PNN

    分子量

    67kDa/81kDa

    基因ID

    5411

    UniProt

    Q9H307
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