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Phospholamban 抗体 (pSer16, pThr17)

This anti-Phospholamban antibody is a 兔 多克隆 antibody detecting Phospholamban in WB. Suitable for 人.
产品编号 ABIN7269330
发货至: 中国

Quick Overview for Phospholamban 抗体 (pSer16, pThr17) (ABIN7269330)

抗原

See all Phospholamban (PLN) 抗体
Phospholamban (PLN)

适用

  • 86
  • 24
  • 22
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宿主

  • 87
  • 3
  • 1

克隆类型

  • 86
  • 5
多克隆

标记

  • 44
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  • 5
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This Phospholamban antibody is un-conjugated

应用范围

  • 37
  • 35
  • 26
  • 26
  • 22
  • 11
  • 10
  • 9
  • 9
  • 9
  • 7
  • 6
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 25
    • 17
    • 11
    • 9
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer16, pThr17

    原理

    Phospho-PLN-S16/T17 Rabbit pAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around of human Phospho-PLN-S16/T17.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Phospholamban (PLN)

    别名

    PLN

    背景

    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.,CMD1P,CMH18,PLB,PLN,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Heart,Contractility,PLN

    分子量

    6kDa

    基因ID

    5350

    UniProt

    P26678

    途径

    Negative Regulation of Transporter Activity
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